nfuse

Introduction Complex Genomic Rearrangements (CGRs) are an important aspect of the genomic landscape of many tumours. CGRs often disrupt genes and fuse other genes, in some cases promoting tumour development. nFuse predicts fusion transcripts and associated CGRs from matched RNA-seq and Whole Genome Shotgun Sequencing (WGSS). See the getting started guide for instructions on how to setup and run nFuse. Publication nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing. McPherson AW, Wu C, Wyatt A, Shah SP, Collins C, Sahinalp SC. Genome Res. 2012 Jun 28. News Don"t Use Ensembl 67 - 01/19/2013 If you study prostate cancer, Ensembl 67 (and possibly other versions) have an erroneous gene encompassing TMPRSS2 and ERG, and you will miss the TMPRSS2-ERG fusion Ensembl 70 does

nfuse-0.2.1
include
tools
scripts
data
external