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_The MPI-HMMER project has moved to a newer, more permanent location. Please visit http://www.mpihmmer.org for the latest news and access to the development source code._
The MPI-HMMER team is pleased to announce the impending release of MPI-HMMER. MPI-HMMER is a multiple-level optimization of the original HMMER 2.3.2 code by Sean Eddy of the HHMI Janelia Farms facility. This optimization provides multiple layers of acceleration, from micro-vectorization of the p7Viterbi algorithm through parallelization using MPI.
The hmmsearch and hmmpfam were refactored from PVM code into MPI code, and various hand optimization and code improvements were made. The resulting code demonstrates good speedup and high parallelism on low latency connected systems with low OS jitter. This new implementation is approximately 4x faster than the PVM version of HMMER, approximately 12x faster than the baseline single CPU tests.
Please see the "Downloads" section for source. RP