资 源 简 介
This project contains R packages for identifying the optimal non-stationary and non-homogeneous Markov model of nucleotide sequence evolution.
BUP: This package enables the identification of the optimal model of rate variation across lineages under the following assumptions - (i) all sites are independent, (ii) a site is either variable or invariable, and (iii) all variable sites are identically distributed. Click here to download the user manual. The user manual contains the links for downloading the package and example dataset.
RAS: This package enables the identification of the optimal model of rate variation across sites for a given model of rate variation across lineages. Therefore, the best model of rate variation across lineages identified using BUP can be provided as an input for determining the best model of rate variation across sites.