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多位点联合模拟

  • 资源大小:5.98 MB
  • 上传时间:2021-06-30
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  • 标      签: 模拟 联合 位点

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The application program mlcoalsim (multilocus coalescent simulations) is designed to: (i) Generate samples and calculate neutrality tests, and other statistics, under stationary model, several demographic models or strong positive selection by mean of coalescent theory. (i) Perform coalescent simulations with the mutational phase given: 1. the population mutation rate θ (θ = 4Nμ, where N is the effective population size and μ is the mutational rate). 2. a fixed number of mutations. 3. a distribution of θ values. A prior uniform (bounded) and a gamma distributions are enabled. 4. a fixed number of biallelic segregating sites taking into account the uncertainty of the population mutation rate (conditioning on biallelic segregating sites). A prior uniform (bounded) and a gamma distributions are enabled. (iii) Perform coalescent simulations with recombination given: 1. the population recombination rate R (R = 4Nr, where r is the recombination rate). 2. a distribution of r values. A prio

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mlcoalsim
.DS_Store
bin
examples
GNU_GPL_License.txt
manual_mlcoalsim.pdf
other_apps
source_files

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