probtf

ProbTF is a software tool for predicting transcription factor binding using experimentally verified Position Weight Matrices (PWMs). The included sets of PWMs are from the TRANSFAC Public 7.0 database ProbTF provides a probabilistic framework for transcription factor binding prediction which has three important features. First, ProbTF is probabilistic in nature and thus outputs a probability of binding (as opposed to a p-value). Second, the method answers the question of whether the whole promoter has a binding site. Third, ProbTF provides a principled way of combining multiple data sources, such as evolutionary conservation, regulatory potential, CpG islands, nucleosome positioning, DNase hypersensitive sites, ChIP-chip, and other prior knowledge, into a unified probabilistic framework. Links Software Description 请点击左侧文件开始预览 ！预览只提供20%的代码片段，完整代码需下载后查看 加载中 侵权举报