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The PLS (Partial Least Squares) and NPAIRS (Nonparametric, Prediction, Activation, Influence, Reproducibility, re-Sampling) neuroimaging software package developed at the Rotman Research Institute.
PLS (Partial Least Squares) was first introduced to the neuroimaging community in 1996 (McIntosh et al., 1996), for measuring distributed task responses (Mean-Centering PLS and Non-Rotated Task PLS). It has also been applied to measuring distributed patterns that impact on task performance (Regular Behav PLS, Non-Rotated Behav PLS and Multiblock PLS) and finally to both task-dependent and resting state regional connectivity (McIntosh and Lobaugh, 2004).
The NPAIRS (Nonparametric, Prediction, Activation, Influence, Reproducibility, re-Sampling) package was first introduced with canonical va
