snape-pooled

SNAPE-pooled Introduction SNAPE-pooled computes the probability distribution for the frequency of the minor allele in a certain population, at a certain position in the genome. Obviously if this probability is high enough, then you have a segregating position, a.k.a. SNP. ## Futher information ## If you want to use SNAPE-pooled, I guess you should first read the paper SNP calling by sequencing pooled samples (Raineri E, Ferretti L, Esteve-Codina A, Nevado B, Heath S, Pérez-Enciso M. , BMC Bioinformatics. 2012 Sep 20;13:239. doi: 10.1186/1471-2105-13-239) which explains the formulae used in it. There is a Postscript manual in the Downloads section of this site. We are distributing the source code, but not an executable : hence you"ll have to create a binary yourself, by using the enclosed Makefile. If you don"t know how to do that, send me an email. SNAPE is not a difficult software to run. The input format is SAMTOOL