资 源 简 介
This pipeline uses a combination of blast to overcome difficulties with current functional gene annotation techniques.
* Uses no E-value cutoff to determine if something is a homolog, to allow for multiple proteins to be compared without difficulty of varying conservancy
* Creates a HMM and consensus sequence of a whole gene, rather than singular conserved domains (e.g. PFAM)
* Runs against nucleotide databases, to avoid issues of orf-calling, but using protein sequences to for better resolution of matches
* Verifies putative homologs against the STRING database to check if the target and the query are in the same COG.
