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您现在的位置是:虫虫源码 > 其他 > 等位基因不平衡表(我),一种新的测量等位基因特异表达的工具

等位基因不平衡表(我),一种新的测量等位基因特异表达的工具

  • 资源大小:23.47 MB
  • 上传时间:2021-06-30
  • 下载次数:0次
  • 浏览次数:1次
  • 资源积分:1积分
  • 标      签: 工具 测量 基因 表达

资 源 简 介

Allim sourceforge For the latest version of Allim go to Sourceforge http://sourceforge.net/projects/allim Introduction Allim, Allelic imbalance meter, offers an integrated and user-friendly solution for measuring allele specific gene expression (ASE) within species. Allim estimates allelic imbalance in F1 hybrids. Since mapping bias is the largest problem for reliable estimates of allele specific gene expression using RNA-seq, Allim combines two different measures to account for mapping biases. First, Allim generates a polymorphism aware reference genome that accounts for the sequence variation between the alleles of both parents (or parental lines). Second, Allim includes a sequence specific simulation tool to estimate the remaining mapping bias. This estimated mapping bias is then incorporated in the statistical tests for allelic imbalance. The pipeline requires whole transcript high throughput RNA sequencing (RNA-seq) reads of F1 hybrids. A

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._Allim_1.1
Allim_1.1
._.DS_Store
.DS_Store
._.RData
.RData
._.Rhistory
.Rhistory
._Allim.py
Allim.py
._AllimOptions_2Pexpr
AllimOptions_2Pexpr
._AllimOptions_2Pgenomes
AllimOptions_2Pgenomes
._classes
classes
._executables
executables

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