资 源 简 介
This tool takes one or more gene sequences and generates any number of single-mutation, neighboring genotypes. You may optionally generate synonymous mutations, non-synonymous mutations or both. Mutations in the sequence"s start and stop codons are excluded. Mutations that generate in-frame stop codons may be included or excluded. Finally, you may select which NCBI translation table to use.
Resulting DNA sequences and their corresponding protein sequences are outputted. Summary statistics for each sequence are also generated: total possible mutations, total valid mutations, and total non- and synonymous mutations.
Genes are provided in the FASTA format, either through file import or direct entry on the user interface. The mutated sequences may be exported to a .fasta file.
Created using:
* Python
* BioPython
* Glade/PyGTK
