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Latest news (Version 0.5.3, 20-Aug-2010)
Vastly improved version of our multiple-mapping deduping script (dedupDiscordants.py). This greatly improves breakpoint calling specificity.
New version of pairDiscordants.py that resolves several minor bugs.
Fixed minor bug in Hydra that occassionally caused false positive calls from readpairs that did not actually support a common breakpoint.
Updated the example workflow page to reflect changes in our pipeline.
Hydra Summary
Hydra detects structural variation (SV) breakpoints by clustering discordant paired-end alignments whose "signatures" corroborate the same putative breakpoint. Hydra can detect breakpoints caused by all classes of structural variation. Moreover, it was designed to detect variation in both unique and duplicated genomic regions
